Highway 65 was closed for almost five hours Friday morning as officials investigated a fatal collision. A 51-year-old woman was pronounced dead on the scene after the 2000 Lexus she was driving collided into a 2008 Ford van just south of Sterling Parkway on Highway 65, according to Lincoln Police Lt. Paul Shelgren. Lincoln police officers were dispatched to the scene just after 5 a.m. on Friday. The woman’s name has not been released, pending notification of next of kin. According to Shelgren, the woman was driving northbound on Highway 65 when her vehicle crossed over into the southbound lane, crashing into the van which contained a driver and three passengers. The van’s passengers were extricated from the van by Lincoln firefighters, who were then taken by ambulance to area hospitals, according to Shelgren. He said the driver, a 47-year-old Lincoln resident and one passenger were transported to Sutter Roseville Hospital with serious injuries, and the other two passengers were transported to Mercy San Juan Hospital. The names of the van’s occupants have not been released. The cause of the crash is currently under investigation, according to Shelgren.